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IBD is comprised of ulcerative colitis (UC) and Crohn’s Disease (CD), the former mainly causing successional shallow ulcers with intestinal crypt abscesses in lamina propria and the latter represented by segmental distributed deep ulcers accompanied with non-caseating granulomas in all layers of the intestinal wall which explained its high tendentiousness in fistulation [2]

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The resulting nanoparticles were purified by dialysis for two days to remove unreacted species and stored at 4 °C for further use