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Females often camouflage their autistic traits by mimicking social behaviors, suppressing stimming, or rehearsing conversations, which can lead to underdiagnosis (Wood-Downie et al., 2021), and thereby significantly impacts the male-to-female incidence ratio ( In this review, we discuss the key characteristic features of ASD, genetic and molecular pathways, the role of nuclear hormone receptors, aspects related to gen therapy, and other therapeutic interventions