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It wasn't until researchers started mapping NNMT activity across different tissue types that its significance became clear: NNMT is markedly overexpressed in the fat tissue of obese animals and humans, and that overexpression tracks closely with metabolic dysfunction

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[DOI] [PubMed] [Google Scholar] 19.Giza CC, Kutcher JS, Ashwal S, Barth J, Getchius TS, Gioia GA, et al