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Abbreviations and Acronyms AAV adeno-associated virus BM basement membrane bFGF basic fibroblast growth factor BAD bcl-2-associated death promoter BV blood vessel BM bone marrow CXCL-10 CXC motif ligand-10 CXCR3 CXC chemokine receptor 3 DAG diacylglycerol EC endothelial cell EPC endothelial progenitor cell ECM extracellular matrix ERK extracellular signal-regulated kinase FAK focal adhesion kinase IP3 inositol 1,4,5-triphosphate IL-8 interleukin-8 KC keratinocyte MAPK mitogen-activated protein kinase MEK mitogen-activated protein kinase/ extracellular signal-regulated kinase kinase NRP neuropilin PI3K phosphatidylinositol 3-kinase PIP 2 phosphatidylinositol 4,5-bisphosphate PIP 3 phosphatidylinositol 3,4,5-triphosphate PLC phospholipase C SPK sphingosine kinase P1GF placental growth factor PDGF platelet-derived growth factor Akt/PKB protein kinase B PKC protein kinase C sVEGFR-1 soluble vascular endothelial growth factor receptor-1 TGF-β transforming growth factor-β TNFSF14/LIGHT tumor necrosis factor superfamily member 14 VEGF vascular endothelial growth factor VEGFR vascular endothelial growth factor receptor Acknowledgments and Funding Sources The authors have received funding from the following sources: National Institutes of Health grants T32GM068412 (K.E.J.) and R01CA127109 (T.A.W.)

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