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chingii Hu provides protection against palmitic acid–induced lipotoxicity in human hepatocyte cell line LO2, which can reduce oxidative stress by preventing the accumulation of reactive oxygen species (ROS), reducing the collapse of mitochondrial membrane potential (MMP), and reducing the decrease of glutathione (GSH) ( Ellagic acid (EA ) seems to play an anti-diabetic activity through the action on β-cells of the pancreas, stimulating insulin secretion and decreasing glucose intolerance ( Studies in cells and rodents have suggested an important role for Raspberry ketone (RK) in hepatic/cardio/gastric protection and as an anti-hyperlipidemic, anti-obesity via mediating activation of PPAR-α ( Raspberry polyphenols have beneficial effects in regulating hepatic lipid metabolism and inflammation in rats with nonalcoholic fatty liver caused by an obesogenic diet ( Pelargonidin-3-O-glucoside derived from raspberry exerts plays a role in regulating blood glucose by inducing autophagy and modulating gut microbiota ( Oleanolic acid (OA) and ursolic acid (UA) are the main characters extracted from R